http://www.ncbi.nlm.nih.gov/pubmed/16047154[*quote*]
Abstract
Eur J Pediatr. 2005 Dec;164(12):758-67. Epub 2005 Jul 27.
Homeopathic treatment of children with attention deficit hyperactivity disorder: a randomised, double blind, placebo controlled crossover trial.Frei H, Everts R, von Ammon K, Kaufmann F, Walther D, Hsu-Schmitz SF, Collenberg M, Fuhrer K, Hassink R, Steinlin M, Thurneysen A.
Source
Swiss Association of Homeopathic Physicians SAHP, Lucerne, Switzerland.
Abstract
An increasing number of parents turn to homeopathy for treatment of their hyperactive child. Two publications, a randomised, partially blinded trial and a clinical observation study, conclude that homeopathy has positive effects in patients with attention deficit hyperactivity disorder (ADHD). The aim of this study was to obtain scientific evidence of the effectiveness of homeopathy in ADHD. A total of 83 children aged 6-16 years, with ADHD diagnosed using the Diagnostic and Statistical Manual of Mental Disorders-IV criteria, were recruited.
Prior to the randomised, double blind, placebo controlled crossover study, they were treated with individually prescribed homeopathic medications. 62 patients, who achieved an improvement of 50% in the Conners' Global Index (CGI), participated in the trial. Thirteen patients did not fulfill this eligibility criterion (CGI). The responders were split into two groups and received either verum for 6 weeks followed by placebo for 6 weeks (arm A), or vice-versa (arm B). At the beginning of the trial and after each crossover period, parents reported the CGI and patients underwent neuropsychological testing. The CGI rating was evaluated again at the end of each crossover period and twice in long-term follow-up. At entry to the crossover trial, cognitive performance such as visual global perception, impulsivity and divided attention, had improved significantly under open label treatment (P<0.0001). During the crossover trial, CGI parent-ratings were significantly lower under verum (average 1.67 points) than under placebo (P =0.0479). Long-term CGI improvement reached 12 points (63%, P <0.0001).
CONCLUSION:
The trial suggests scientific evidence of the effectiveness of homeopathy in the treatment of attention deficit hyperactivity disorder, particularly in the areas of behavioural and cognitive functions.
Homeopathic treatment of children with attention deficit disorder: a randomized, double blind, placebo-controlled crossover trial. H. Frei R. Everts, K.v. Ammon et al. Eur J Pediatr. 2005; 164: 758-767. [Eur J Pediatr. 2007]
PMID: 16047154 [PubMed - indexed for MEDLINE]
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Das muß man sich mal vorstellen: Da wird VOR der Studie den Kindern Homöopathie verabreicht. Jene, die angeblich darauf reagieren, nimmt man in die Studie, die anderen werden abgewiesen.
[*quote*]
Prior to the randomised, double blind, placebo controlled crossover study, they were treated with individually prescribed homeopathic medications. 62 patients, who achieved an improvement of 50% in the Conners' Global Index (CGI), participated in the trial.[*/quote*]
Für gewöhnlich nennt man so etwas Wissenschaftsbetrug. Zielorientierte Selektion der Probanden ist eines der beliebtesten Mittel der Fälschung.
Davon abgesehen ist die Zahl der Probanden sowieso zu klein.
Verhaltensstörungen wie ADHS sind starken Schwankungen unterworfen. Wie will man die sinnvoll messen? Vor allem ist wesentlich, WER die Auswertungen macht. "Voreingenommenheit" ist noch milde, ist aber als "bias" in der medizinischen Forschung ein wesentlicher Knackpunkt, der extrem genau beachtet werden muß.
