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Dr. Luis David Lemus AcuñaCountry of Origin
Chile
Education and Professional Experience
Professional Degree from the Veterinary Medical (VMD), University of Chile
Academic Degree from the Doctor Vet Science, Madrid University, Spain
After completing his educational degrees, Dr. Lemus professional experience has devoted his efforts to
furthering science and medicine as the Director of Morphology at the University of Chile, where he later
became a Full Professor or Histology and Embryology.
Accomplishments
Professor invited University of Madrid, 1982, 1988
Foreign Academic Member of Real Academy of Vet., Spain Institute, 1988
Awards
HWO Fellowship, Complutense University of Madrid, 1974-1975
Award to the Best Thesis to obtain the Doctor Degree in Veterinary Sc. (Cum Laude,) Hispanic Culture
Institute, 1975
Recent Publications
D. Lemus et al. Effect of Morinda citrofolia (Tahitian Noni Juice, TNJ) on angiogenesis and tumor growth in
carrier mice of tumor TA3-MTX-R. (Phytotherapy Research), May 2004.
M. Molina, V. Ferreira, C. Valk, J. Orellana, A. Rojas, R. Billeta, D. Lemus, A. Ferreira (2004). An in vivo
role for Trypanosoma cruzi calreticulin in antiangiogenesis. Sent to Mol. Biochem. Parasitol.
J.P. Castillo, M. Fuenzalida, D. Lemus, A. Guerrero (2003) Actividad antineoplásica y antimestásica de la
asociación de betametasona, sulindac y oxytetraciclina. Rev. Chil CancerologÃa Y HematologÃa Vol 13:
41-48.
J.Zúñiga, M.Fuenzalida, A.Guerrero, J.Illanes, A.Dabancens, E.DÃaz and D.Lemus (2003) Effects of
steroidal and non steroidal drugs on the neovascularization response induced by tumoral TA3 supernatant on
CAM from chick embryo. Biol Res 36 :233-240.
J.Illanes, A.Dabancens, O.Acuña, M.Fuenzalida,A.Guerrero, C.López and D.Lemus (2002). Effects of
betamethasone, sulindac and quinacrine drugs on the inflammatory neoangiogenesis response induced by
polyurethane sponge implantes in mouse. Biol. Res. 35: 339-343, 2002.
L.Strauss, M.Fuenzalida, J.Illanes, A.Dabancens, E.DÃaz, A.Guerrero and D.lemus (2002). Effect of sulfated
-cyclodextrin, a water soluble cycloamylose, on the promotion and/or inhibition of angiogenesis. Pathol. Oncol.
Res. Vol 8, 1:47-53.
D. Lemus, A. Dabancens, J. Illanes, M. Fuenzalida, A. Guerrero y P. Gonzalez (2001). "Antiangiogenesis
effect of betamethasone on the chick CAM stimulated by TA3 tumor supernatant". Biol. Res 34:227-236.
Guerrero,A., Dabancens,A., Zipper,J., Lemus,D. (1999) Regresión de tumor transplantable mediante la
administración de quinacrina mas indometacina oral en raton AJ. Rev.Chil.Citol.Vol.3:20-23.
Guerrero,A., Diaz-Muñoz,C., Dabancens,A., Lemus,D., Fuenzalida,M., Illanes,J., Zipper,J. (1998) Actividad
antineoplásica y antimestásica de la quinacrina en combinación co ketoprofeno, betametasona y levamisol
en tumores TA3 transplantables de ratón. Rev.Chil.Cancerol. y hematol.8:169-176.
Location/ Hometown
Chile
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Dr. Chi-Tang HoEducation and Professional Experience
BS, Chemistry, National Taiwan University
MA, Organic Chemistry, Washington University
PhD, Organic Chemistry, Washington University
Dr. Chi Tang Ho received his PhD in Organic Chemistry in 1974 and immediately started working
professionally as a researcher and professor in the Food Science Department at Rutgers University. He is now
Director of the food science graduate program at Rutgers University in New Jersey.
Accomplishments
Dr. Ho has written over 140 book chapters on different topics related to science and nutrition. Additionally he
has received 5 U.S. patents related to nutrition. He has been an associate editor for the Journal of Food
Science, and served on the editorial boards of many food industry publications. He is currently the senior editor
at Molecular Nutrition and Food Research. From the year 2000 Dr. Ho has been an honorary professor at
universities in China. Currently he is an honorary professor at the China Agricultural University in Beijing.
Awards
IFT Stephen S. Chang Award for Lipid or Flavor Science: Institute of Food Technologists
Board of Trustees Award for Excellence in Research at Rutgers, The State University of New Jersey: Rutgers
University
Cited as â œHighly Cited Researcherâ in Agricultural Sciences: Institute for Scientific Information
Spotlight Award for Research Excellence: Cook College, Rutgers University
Fellow Award: Agricultural and Food Chemistry Division, American Chemical Society
American Chemical Society Newsmaker for Research in an ACS Journal Award
Distinguished Service Award: Agricultural and Food Chemistry Division, American Chemical Society
Platinum Award: Agricultural and Food Chemistry Division, American Chemical Society, 1994 & 1995
Publications
Dr. Wong is widely published having written over 334 publications in scientific and medical journals. He has
specialized in nutraceutical discovery and development including the unique properties of the noni plant. The
following is a list of publications Dr. Ho has published which contribute to noni research.
Wang, Mingfu; Kikuzaki, Hiroe; Csiszar, Katalin; Boyd, Charles D.; Maunakea, Alika; Fong, Sheri F. T.; Ghai,
Geetha; Rosen, Robert T.; Nakatani, Nobuji; Ho, Chi-Tang. Novel trisaccharide fatty acid ester identified from
the fruits of Morinda citrifolia (Noni). Journal of Agricultural and Food Chemistry 1999, 47, 4880−4882.
Wang, Mingfu; Kikuzaki, Hiroe; Jin, Yi; Nakatani, Nobuji; Zhu, Nanqun; Csiszar, Katalin; Boyd, Charles D.;
Rosen, Robert T.; Ghai, Geetha; Ho, Chi-Tang. Novel glycosides from noni (Morinda citrifolia). Journal of
Natural Products 2000, 63, 1182−1183.
Sang, Shengmin; He, Kan; Liu, Guangming; Zhu, Nanqun; Wang, Mingfu; Jhoo, Jin-woo; Zheng, Qunyi; Dong,
Zigang; Ghai, Geetha; Rosen, Robert T.; Ho, Chi-Tang. Citrifolinin A, a new unusual iridoid with inhibition of
Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.). Tetrahedron Letters 2001, 42,
1823−1825.
Sang, Shengmin; He, Kan; Liu, Guangming; Zhu, Nanqun; Cheng, Xiaofang; Wang, Mingfu; Zheng; Qunyi; Dong,
Zigang; Ghai, Geetha; Rosen, Robert T.; Ho, Chi-Tang. A new unusual iridoid with inhibition of Activator
Protein-1 (AP-1) from the leaves of Morinda citrifolia L. Organic Letters 2001, 3, 1307−1309.
Sang, Shengmin; Cheng, Xiaofeng; Zhu, Nanqun; Wang, Mingfu; Jhoo, Jin-Woo; Stark, Ruth E.; Badmaev,
Vladimir; Ghai, Geetha; Rosen, Robert T.; Ho, Chi-Tang. Iridoid glycosides from the leaves of Morinda
citrifolia. Journal of Natural Products 2001, 64, 799−800.
Liu, Guangming; Bode, Ann; Ma, Wei-Ya; Sang, Shengmin; Ho, Chi-Tang; Dong, Zigang. Two novel glycosides
from the fruits of Morinda citrifolia (Noni) inhibit AP-1 transactivation and cell transformation in the mouse
epidermal JB6 cell line. Cancer Research 2001 61, 5749−5756.
Sang, Shengmin; Liu, Guangming; He, Kan; Zhu, Nanqun; Dong, Zigang; Zheng, Qunyi; Rosen, Robert T.; Ho,
Chi-Tang. New unusual iridoids from the leaves of noni (Morinda citrifolia L.) show inhibitory effect on
ultraviolet B-induced transcriptional Activator Protein-1 (AP-1) activity. Bioorganic and Medicinal Chemistry
2003, 11, 2499−2502.
Noni Research
Dr. Hoâ ™s research is related to the studying of noni. He has identified chemical components of noni fruit,
leaves, and roots.
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Dr. Chen Su
Senior Scientist
Senior Manager
Research and Development Team
Tahitian Noni International Country of Origin
China
Education and Professional Experience
B.S. in chemistry from Xiamen University of China;
Ph.D. in chemistry from University of Utah.
Dr. Chen Suâ ™s professional career began as an auditor for the Environment Protection Bureau of Xiamen,
China. She moved on to work as an analytical chemist for DetaChem Laboratory in Salt Lake City, Utah and
then as a scientist and analytical specialist for a pharmaceutical company. Her career emphasis and dedication
is now as a Senior Scientist and Senior Manager to Tahitian Noni Internationalâ ™s Research and
Development team.
Publications related to Noni research
An ethanol insoluble precipitate of Morinda citrifolia (Noni) fruit juice (NoniPPT) and its
anti-metastatic effects published in Proceedings of 95th Annual Meeting of American Association for
Cancer Research.
A new selective COX-2 inhibitor: Morinda citrifolia (Noni) published in Proceedings of 7th
international conference of eicosanoids and other bioactive lipids in cancer, inflammation and related
diseases.
Cancer Preventive Effect of Morinda citrifolia (Noni) published in Annals of the New York Academy
of Science.
Morinda citrifolia (Noni): A literature review and recent advances in Noni research published in Acta
pharmacologica sinica.
Protective effects of Morinda citrifolia (Noni) on plasma SAR and LPO in current smoker in proceeding
of XI Biennial meetings of the society for free radical research.
Link to Noni research: pubmed.com
Location/ Hometown
West Jordan, Utah
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Dr. Bing Nan Zhou
Senior Research Scientist
Senior Manager
Research and Development Team
Tahitian Noni International Country of Origin
P.R. China
Education and Professional Experience
Bing-Nan Zhou obtained PhD in Graduated School of Shanghai Institute of Materia Medica, Academy of
Sciences in 1964 and was appointed as Research Associate, Associate Professor and Professor in Shanghai
Institute of Materia Medica, Academy of Sciences (1964-1994). In 1989, he was directly nominated as
Advisor of PhD Candidates by Academic Degree Committee of State Council of China. Under his guidance
four graduate students received their PhD degree and 12 graduate students received their MS degree. He
received training in Institute of Bio- and Organic Chemistry, Czechoslovak Academy of Sciences (1961-1962)
at Prague and Post-Doctor position in School of Pharmacy, University of Wisconsin (1981-1983). As visiting
Professor he visited Department of Chemistry of British Columbia (1997) at Vancouver, Canada, College of
Pharmacy, University if Illinois at Chicago (in 1987, 1990, 1991, 1992 and 1993). He worked in Department of
Chemistry, Virginia Tech as Senior Research Scientist (1994-2002). Now he is appointed as Senior Research
Scientist in Tahitian Noni International.
Awards
Natural Sciences Award (2nd) from Chinese Academy of Sciences & Ministry of Sciences and Technology of
China (1987)
Research Award (2nd) from National Committee of Family Planning of China (1993)
Receiving allowance from State Council of P. R. China for his excellent contributions to the research on
Chinese Traditional Herbs and Natural Organic Chemistry (1998 - now)
Publications
Dr. Zhou has published more than 150 research papers and 5 professional books on natural products in
chemistry. He is a reviewer of Journal of Natural Products (USA), Planta Medica (Germany), and
Phytochemistry (UK).
He has given 25 plenary lectures on the international meeting at Rio de Janeiro, Brazil; Seoul, Korea; Lausanne,
Switzerland; Karachi, Pakistan; Chicago, USA; Hong Kong, Shanghai and Beijing, China. He has also been
invited to give lectures in Schering-Plough Research Institute, NJ, Merck Pharmaceutical Research Institute, NJ,
and College of Pharmacy, University of Rhode Island (Kingston, RI).
Related Noni Research
Research on Noni Leaf Serum: finished Isolation of pure bioactive compounds from Noni Leaf and
manufactory process for making Noni Leaf extract for Noni Leaf Serum. The studies on the structures
of its bioactive compounds are in progress.
Research on the phyto-estrogenic compound fro Noni juice: A compound with strong phyto-estrogenic
bioactivity has been isolated and the study on its structure is in progress after further purification.
Found COX2 bioactive compounds from Noni juice in polar fraction and the study is in progress.
Researches on MangoXan: Finished isolation of the bioactive compounds â “ ï ¡-Mangostin, ï
¢-Mangostin, and ï §-mangostin from Mangostin fruit and made their standard samples for its qualitative
analysis. Figured out its qualitative analysis for validation and suggested the method to improve its
formulation.
Found a compound, which can inhibition cancer cell line in vitro from Noni juice and finished its
structure study.
Noni Motivation
â œNature is a treasure and provides mankind with food, nutrition, and medicine. Noni is a present and every
part is useful for people. Since very ancient times, Noni has brought Tahiti people health, strong bodies, and
happiness. Now we are learning Tahitian heritage and make great efforts to discover its secret. By using
current modern scientific technology, we are trying to develop new products and find the reason why Noni can
benefit human beings, besides guaranteeing the quality of our products.â
Location/ Hometown
Pleasant Grove, Utah
Xu-Hui District, Shanghai, P. R. China
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Dr. Anne Hirazumi-Kim
Senior Research Scientist
Spokesperson
Tahitian Noni InternationalCountry of Origin
Japan
Education and Professional Experience
Dr. Hirazumi-Kim grew up in California and Japan as the youngest child in an Air Force family. She first
became interested in Noni when, in 1989, she gave some juice to her dog Brownie, who was very sick.
In 1990, Dr. Hirazumi earned her bachelors degree with high honors in chemistry from the University of Hawaii.
She eventually became interested in pharmacology. She worked with Dr. Furusawa at Leahi Hospital, studying
the mechanism by which the Noni fruit appeared to be working in animals. She earned a Ph.D. in Pharmacology
at the University of Hawaii, 1997. Her research for her Ph.D. dissertation demonstrated the anti-tumor activity
of Noni fruit juice.
Publications
Hirazumi A, et al. â œAn immunomodulatory polysaccharide-rich substance from the fruit juice of morinda
citrifolia (noni) with antitumour activity.â Phytother Res. 1999 Aug; 13(5):380-7.
Hirazumi A, et al. â œImmunomodulation contributes to the anticancer activity of morinda citrifolia (noni) fruit
juice.â Proc West Pharmacol Soc. 1996; 39:7-9.
Hirazumi A, et al. â œAnticancer activity of Morinda citrifolia (noni) on intraperitoneally implanted Lewis lung
carcinoma in syngeneic mice.â Proc West Pharmacol Soc. 1994; 37:145-6.
Location/ Hometown
Hawaii
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Brett West
Director
Noni Benefits Research
Tahitian Noni InternationalCountry of Origin
United States
Education and Professional Experience
Bachelor of Science, Zoology / Molecular Biology, Brigham Young University
Master of Science, Pharmacology and Toxicology, University of Arizona
Brett West has worked with the Research and Development team at Tahitian Noni International since
1997,researching the benefits of noni.
Accomplishments
Approval of TAHITIAN NONI© Juice as a safe novel food within the European Union
Several awarded andpending United States patens relative to Morinda citrifolia
Awards
Graduate school scholarship and National Institute of Occupational Safety and Health (NIOSH) stipend.
Publications, Presentations, and Patents
West BJ, Tolson CB, Vest RG, Jensen S, Lundell TG. Mineral variability among 177 commercial noni
juices. International Journal of Food Sciences and Nutrition 2006 Publication pending.
West BJ, Jensen CJ, Westendorf J, and White LD. A Safety Review of Noni Fruit Juice. Journal of Food
Science 2006 October; 71(

:R100-R106.
(
http://www.blackwell-synergy.com/doi/full/10.1111/j.1750-3841.2006.00164.x)
West BJ. Hepatotoxicity from interferon-beta not noni juice. Digestion 2006;74:47-48.
West BJ, Jensen CJ, Westendorf J. Noni juice is not hepatotoxic. World J Gastroenterol 2006 June 14;
12(22):3616-3619. (
http://www.wjgnet.com/1007-9327/12/3616.asp)
Palu AK, West BJ, Jensen J, White L. Knowing your noni tree and traditional usage eliminates confusion.
Biochem Biophys Res Commun. 2006 Dec 22;351(3):577. Epub 2006 Nov 7.
Palu AK, West B, Jensen J. Not all noni liquid dietary supplements are created equal. American Journal
of Hematology 2005 May;79(1):81.
Wang MY, West BJ, Jensen CJ, Nowicki D, Su C, Palu AK, Anderson G. Morinda citrifolia (Noni): a
literature review and recent advances in Noni research. Acta Pharmacol Sin. 2002 Dec;23(12):1127-41.
(
http://www.chinaphar.com/1671-4083/23/1127.pdf)
Brett J West and Afa Palu. Evaluation of the allergenic potential of Morinda citrifolia L. leaf proteins.
AGFD 158. The 232nd American Chemical Society National Meeting, San Francisco, CA. September
10-14, 2006
(
http://oasys2.confex.com/acs/232nm/techprogram/P950562.HTM)
Shixin Deng, Afa K Palu, Bing-Nan Zhou, Jarakae C. Jensen, and Brett J West. Noni contains competitive
ligand(s) binding to GABAa agonist receptors as an anxiolytic. AGFD 67. The 232nd American
Chemical Society National Meeting, San Francisco, CA. September 10-14, 2006.
(
http://oasys2.confex.com/acs/232nm/techprogram/P995203.HTM)
Afa K. Palu, Bing-Nan Zhou, Shixin Deng, and Brett J. West. Morinda citrifolia L. Noni: An angiotensin
converting enzyme inhibitor. AGFD 130. The 232nd American Chemical Society National Meeting, San
Francisco, CA. September 10-14, 2006.
(
http://oasys2.confex.com/acs/232nm/techprogram/P974821.HTM)
Shixin Deng, Afa Palu, Bin-nan Zhou, Chen Su, Jarakae Jensen, Brett West. Constituents of the fruit of
noni and their Selective inhibitory effects of cyclooxygenase-2 enzyme. The 47th Annual Meeting of the
American Society of Pharmacognosy. August 5-9, 2006. Arlington, Virginia.
(
http://www.phcog.org/AnnualMtg/Posters.html)
Afa K. Palu, Chen Sus, Bing-nan Zhou, Brett West, Shixin Deng, Jarakae Jensen. The inhibitory effects
of Morinda citrifolia L. noni on phosphodiesterase enzymes: The possible mechanisms for increasing
energy and improving diabetic conditions. CIPAM 2006 Abstracts. IVth International Conference on
Aromatic and Medicinal Plants from French Overseas Regions. Tahiti. July 10-13, 2006. p. 12.
Chen Su, Brett J. West, â ˜Afa K. Palu, Bing-nan Zhou, Jarakae Jensen, John Fritz, Anne Hirazumi-Kim.
Inhibition of tumar metastasis by the ethanol insoluble precipitate from Morinda citrifolia (L) fruit juice
and its possible mechanism. CIPAM 2006 Abstracts. IVth International Conference on Aromatic and
Medicinal Plants from French Overseas Regions. Tahiti. July 10-13, 2006. p. 28.
Afa Kehaati Palu, Brett Justin West, Jarakae Jensen, Bing-nan Zhou. Morinda citrifolia L. Noni has
cholesterol lowering potential. The 47th Annual Meeting of Society for Economic Botany, Folk Botanical
Wisdom; Towards Global Markets. June 5-9, 2006. Final Program, page 71
(
www.econbot.org/events/2006/SEB2006%20Program.pdf).
Chen Su, Anne Kim, Afa K. Palu, Brett West, Jarakae Jensen. The phytoestrogen effect of Morinda
citrifolia (Noni). Proceedings of WorldNutra 2004, 5th International Conference and Exhibition on
Nutraceuticals and Functional Foods, November 7-10, 2004, San Francisco. Page 471
(
www.worldnutra.com/pdetails2004.htm).
Chen X. Su, Mina Y Wang, C. Jarakae Jensen, Anne H. Kim, Brett West, Summer Jensen, Afa Palu,
Bing-Nan Zhou, Johnathan W Fritz. An ethanol insoluble precipitate of Morinda citrifolia (Noni) fruit
juice (NoniPPT) and its anti-metastatic effects. Proceedings of the American Association for Cancer
Research, Vol. 45 March 2004:29.
Method and formulation for treating candidiasis using Morinda citrifolia. United States Patent 7,014,873.
West, Brett Justin; et al. March 21, 2006.
Freeze concentration process. United States Patent 6,855,354. Jensen, Claude Jarakae; West, Brett J.;
Ogden, Robert V.; Story, Stephen P.
Methods and compositions for reactivating acetylcholinesterase. United States Patent Application
20050260291. Palu, Afa Kehaati; West, Brett; Zhou, Bing-Nan; Jensen, Jarakae; Story, Stephen.
Morinda citrifolia-based formulation for inhibiting metastasis of carcinogenic cells. United States Patent
Application 20050106275. Su, Chen; West, Brett Justin; Palu, Afa Kehaati; Hirazumi-Kim, Anne; Jensen,
Claude Jarakae; Story, Stephen P.
Selectively inhibiting estrogen production and providing estrogenic effects in the human body. United
States Patent Application 20040224038. Wang, Mian Ying; Su, Chen Xing; Palu, Afa Kehaati; Zhou,
Bing-Nan; West, Brett Justin; Westendorf, Johannes Joseph; Jensen, Claude Jarakae; Story, Stephen Paul.
Preventative and treatment effects of Morinda citrifolia as an aromatase inhibitor. United States Patent
Application 20040192761. Palu, Afa Kehaati; West, Brett Justin; Jensen, Claude Jarakae; Su, Chen;
Zhou, Bing-Nan; Story, Stephen P.
Morinda citrifolia as a 5-Lipoxygenase inhibitor. United States Patent Application 20040191341. Palu,
Afa Kehaati; West, Brett; Jensen, Claude Jarakae; Su, Chen; Zhou, Bing-Nan; Story, Stephen P.
Noni Motivation
"Studying a tropical fruit was not something I imagined myself doing, even while finishing my formal education.
However, this has turned out to be a much better opportunity than any of my other plans, and what an education
it has been! It has been the opportunity of a lifetime to be one of the 'discoverers' of the many aspects of the
impressive noni plant."
Location/ Hometown
Brett was born and raised in California, lived two years in Pennsylvania, and attended graduate school in
Arizona. Since then he has lived in Utah and currently resides in Orem.
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